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c/glp1muscle·posted 1 year ago by u/incretin_ivy

[Question] DEXA — what am I missing here

Question Cold Box ×8 Clean Column ×3

Trying to get a straight answer on this: DEXA — what am I missing here.

How to make a DEXA comparison mean anything.

Same machine, same clinic, same protocol. Same hydration and fasting state, as far as you can manage. At least three to four months apart, because the measurement error is large relative to short-term change. Three scans rather than two, because the first pair cannot distinguish a trend from noise.

Do less than that and you have two numbers with an offset of unknown size, which people then react to by rebuilding a training programme. The free alternative — a few tracked lifts and a monthly waist measurement — is directionally informative, costs nothing, and is far harder to over-interpret.

What the evidence actually supports, stripped of the arguing.

Some lean mass is lost in any weight-loss deficit. Resistance training and adequate protein intake are the two interventions with real support for limiting the proportion. Nearly everything else discussed on this board is a rounding error on those two.

The complication specific to this site is that appetite reduction makes protein intake a logistics problem: you are being asked to eat a fixed amount of something at exactly the point when eating anything is less appealing. That is why the practical threads here are about timing and food choice rather than motivation, and why measuring intake rather than estimating it is the single most common useful correction.

Three scans over eighteen months, same machine, same conditions. Only the third one made the first two interpretable.

Corrections welcome, especially the pedantic ones. Pedantry is how this board earns its reputation.

2,594 up / 145 down95% upvoted49 commentsid 3h07iz11 May 2025

49 comments

21 in this archive, depth 6

best — the order this archive was captured in

u/milos_vestergaard161 points·1 year ago

Hydration status and fasting state affect the lean mass estimate. Standardising both is the difference between a comparison and a coin toss.

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u/arne_amankwah192 points·1 year ago

Fat-free mass index is a ratio of fat-free mass to height squared. It moves when either term does, which makes it awkward to interpret during active weight change.

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u/tomas_kimani100 points·1 year ago

Nothing here is a training or nutrition prescription. Targets and programmes are matters for somebody who knows your history and your training background.

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u/trialwatch_theotrial nerd69 points·1 year ago

Lost slower for six months deliberately and my composition change was not obviously different. Training was what mattered.

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u/kenji_vasquez0 points·1 year ago·edited

Lost slower for six months deliberately and my composition change was not obviously different.

Disagreeing with this line: rate alone does not preserve lean mass. The training does.

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u/halima_mbeki36 points·1 year ago

This. Same machine, same protocol, or the DEXA comparison is measuring the scanner.

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u/diego_iyer9 points·1 year ago·edited

What is protein intake actually looking like, measured rather than estimated?

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u/emil_okwuosa3 points·1 year ago

protein and resistance training, that is the entire intervention

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u/titration_marshalmod · c/semaglutide5 points·1 year ago

That protein figure is grams per day, not grams per kilogram. Different claim entirely.

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[removed]4 points·1 year ago

[removed by moderator]

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u/sanne_novak0 points·1 year ago

Agreed — protein and resistance training. Everything else in these threads is a rounding error on those two.

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u/line_demir24 points·1 year ago

Same. Volume over novelty. Changing programme every six weeks cost me a year.

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u/matias_falk9 points·1 year ago

Not convinced by that DEXA comparison. Different machine, different protocol, and the difference is inside the error.

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u/ferran_dahlberg4 points·1 year ago

Are you comparing against your own baseline or against a published average?

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u/andres_restrepo1 point·1 year ago

Yes. Nobody here is prescribing training or nutrition and the good posts say so.

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u/viktor_laurent0 points·1 year ago

Not convinced by that DEXA comparison.

Adding the free proxy — track a few lifts monthly. It costs nothing and it is longitudinal.

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u/tidy_vialdrawer_watch25 points·1 year ago

On comparing yourself to composition figures from trials.

Published composition data comes from supervised populations with structured protocols, standardised scanning, and analysis populations that have been defined in advance. Your two scans at a local clinic, taken in different states of hydration, are not the same measurement.

Use your own baseline. The question worth asking is whether your own trajectory is going the way you want given what you are actually doing, and the honest answer usually requires measuring protein rather than estimating it and being truthful about training frequency. Neither of those is advice — a programme and a target are things to work out with somebody who knows your history.

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u/incretin_ivyOPpharmacology14 points·1 year ago

What was the rate of weight change over that window?

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u/meera_oyelaran9 points·1 year ago

What was the rate of weight change over that window?

Agreed — and same machine, same conditions, or the two scans are not comparable.

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u/plain_titration11 points·1 year ago

Fasted and hydrated the same way for both scans?

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u/noor_ivaturi12 points·1 year ago

Kept the same programme for a year instead of changing it every six weeks. That was the change that worked.

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Lean-mass retention during rapid weight loss: protein targets, resistance-training minimums, DEXA and BIA measurement reality, FFMI tracking, and the sarcopenia question that nobody funded a proper trial for.

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