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c/compounding·posted 5 days ago by u/neha_krastev

[Explainer] why "compounded" does not mean "generic"

Explainer

Genuinely asking, not being difficult.

Everyone in c/hplc repeats that shortage list is important. I believe it, but I have never seen anyone show why, and when I search I get 9 threads of people agreeing with each other.

Is there a paper? Is there a measurement? Or is this one of those things that is true because it has been repeated since 2023?

I am not trying to be the "source?" guy. I would just like a source.

1,793 up / 1,582 down53% upvoted23 commentsid 1lmuup24 Jul 2026

23 comments

17 in this archive, depth 5

best — the order this archive was captured in

u/formulary_fighterMOD46 points·4 days ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/ignacio_vanhecke11 points·4 days ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/prior_auth_painappeals32 points·4 days ago

Strongly agree. API source transparency matters.

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u/joaquin_trevino25 points·4 days ago·edited

shortage list status is telehealth, check the actual list

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u/nadia_fonseca13 points·4 days ago

This is correct. The shortage list does expire and the rules change.

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[removed]10 points·4 days ago

[removed by moderator]

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u/camila_mensa3 points·4 days ago

the 503A/503B distinction is load-bearing, do not blur it

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u/bruno_dumitru16 points·4 days ago

Flair changed to match the content.

Adding to this: shortage list is doing more work than the comment implies.

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u/stubborn_batchlist_pls11 points·4 days ago

telehealth prescriber models exist, pricing differs by state

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u/formulary_fighterappeals6 points·4 days ago·edited

Not to be pedantic but 503B and telehealth are being used interchangeably and they are not interchangeable in real life.

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u/slow_logbook7 points·4 days ago

telehealth prescriber models exist, pricing differs by state

Yes, exactly this, and it is the bit that took me 34 weeks to accept.

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u/neha_krastevOP6 points·4 days ago

Moved states and the compounding landscape changed completely. Different rules, different pharmacies, different costs.

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u/tove_ogunleye23 points·4 days ago

Not to be pedantic but shortage list and 503A are being used interchangeably and they are not interchangeable in real life.

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u/clara_danquah54 points·4 days ago

Flair changed to match the content.

Disagree on that part. 97.9% and 97.6% on the same vial is normal.

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u/priya_palacios30 points·4 days ago

no pharmacy referral codes, naming is fine, recruiting is not

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u/santiago_rasmussen-28 points·4 days ago

Strongly agree. API source transparency matters.

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u/zaid_grimaldi1 point·4 days ago

the 503A/503B distinction is load-bearing, do not blur it

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About c/compounding

Compounded GLP-1s as a supply route: the 503A/503B distinction, the shortage-list mechanics that made compounding legal and then didn't, state board rules, telehealth prescriber models, and what a compounding pharmacy will and will not tell you about its API source.

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  1. Regulatory claims need a citation to the actual rule, notice or docket.
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