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c/compounding·posted 13 days ago by u/hassan_chowdhury

[Discussion] the compounding gap was a symptom, not a solution

Discussion Clean Column ×2

Genuinely asking, not being difficult.

Everyone in c/glp1canada repeats that 503B is important. I believe it, but I have never seen anyone show why, and when I search I get 2 threads of people agreeing with each other.

Is there a paper? Is there a measurement? Or is this one of those things that is true because it has been repeated since 2023?

I am not trying to be the "source?" guy. I would just like a source.

786 up / 124 down86% upvoted30 commentsid 1kiwfx17 Jul 2026

30 comments

26 in this archive, depth 5

best — the order this archive was captured in

u/vikram_mbeki151 points·12 days ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/rohan_steiner-17 points·12 days ago

state board rules differ, say which state

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u/marit_mwangi1 point·12 days ago

API transparency is the question that separates good compounders from sketchy ones

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u/ferran_mensah45 points·12 days ago·edited

Yeah, 503A and 503B are different regulatory animals.

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u/gallbladder_gary15 points·11 days ago

Did they tell you their API source or dodge the question?

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u/niels_roos111 points·11 days ago

regulatory claims need a citation to the actual rule, not interpretation

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u/emil_okwuosa51 points·12 days ago

state board rules differ, say which state

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u/hassan_chowdhuryOP20 points·11 days ago

Are we talking 503A or 503B?

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u/elise_ramos11 points·11 days ago

API transparency is the question that separates good compounders from sketchy ones

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u/usp_appendixMOD26 points·11 days ago

Tracking number removed. It identifies both ends of a shipment.

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u/ahmed_fonseca20 points·11 days ago

The confident tone is doing a lot of work that the evidence is not.

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u/joaquin_trevino14 points·11 days ago

API transparency is the question that separates good compounders from sketchy ones

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[deleted]7 points·11 days ago

[deleted]

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u/marit_mwangi11 points·11 days ago

The confident tone is doing a lot of work that the evidence is not.

Yes, exactly this, and it is the bit that took me 26 weeks to accept.

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u/stubborn_batchlist_pls7 points·11 days ago

Not to be pedantic but 503A and state board are being used interchangeably and they are not interchangeable in real life.

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u/emeka_chowdhury30 points·11 days ago

Strongly agree. API source transparency matters.

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u/enzo_ferrari25 points·11 days ago

the shortage list is temporary, it ends and compounding becomes illegal again

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u/hassan_chowdhuryOP11 points·10 days ago

the shortage list is temporary, it ends and compounding becomes illegal again

Disagree on that part. 97.4% and 96.2% on the same vial is normal.

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u/burned_once_twice36 points·11 days ago

Strongly agree. API source transparency matters.

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u/santiago_rasmussen27 points·11 days ago

Which state? Rules vary.

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u/receptor_bias_rick27 points·11 days ago

Crossposting this to c/maintenancephase because the people who need it are not reading this community.

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u/stubborn_batchlist_pls12 points·11 days ago

shortage list status is state board, check the actual list

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u/rt_shift_reggie6 points·11 days ago

API source questions are on-topic and compounders dodging them is newsworthy

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u/quiet_moderatormod5 points·10 days ago

Not to be pedantic but compounding and 503B are being used interchangeably and they are not interchangeable in real life.

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u/niels_roos6 points·11 days ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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About c/compounding

Compounded GLP-1s as a supply route: the 503A/503B distinction, the shortage-list mechanics that made compounding legal and then didn't, state board rules, telehealth prescriber models, and what a compounding pharmacy will and will not tell you about its API source.

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c/compounding rules
  1. Regulatory claims need a citation to the actual rule, notice or docket.
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