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243
c/coldchain·posted 17 days ago by u/cesar_teixeira

[Failure] vendor packed a cold box with no thermal mass. just foam and hope.

Failure

Week 77 update. 28kg down from the start, early fullness basically gone since about week 34.

Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with early fullness.

The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.

Happy to answer anything. Please do not ask me what dose you should be on.

314 up / 71 down82% upvoted25 commentsid qxohdr12 Jul 2026

25 comments

20 in this archive, depth 5

best — the order this archive was captured in

u/split_dose_sceptic27 points·16 days ago

customs clearance often breaks the cold chain, factor that in

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u/mod_cold_roomMOD14 points·16 days ago

Tracking number removed. It identifies both ends of a shipment.

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u/low_appetite_lisa7 points·15 days ago

Yeah, data logger is the only acceptable proof.

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[removed]4 points·15 days ago

[removed by moderator]

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u/preservative_free_p20 points·16 days ago

France to France takes 5 days on average, variance is 16 days

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u/sequence_checkerresearch peptides17 points·15 days ago

Logger trace from my shipment: 13 hours at 28°C. Powder tested 96.8% against 94.2% claim. Tolerates more than the box implies.

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u/brigade_detector11 points·15 days ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/cesar_teixeiraOP8 points·14 days ago

Spain to Spain takes 21 days on average, variance is 13 days

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u/low_appetite_lisa2 points·14 days ago

This is correct. Dry powder is way more robust than liquid.

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u/solene_abubakar6 points·14 days ago

time-at-temperature integral is the dose, not just peak temperature

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u/elodie_kuipers4 points·15 days ago

You have restated the marketing copy. What is the actual substance here.

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u/honest_syringe333 points·15 days ago·edited

France to France takes 18 days on average, variance is 25 days

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u/phase_two_pete2 points·15 days ago

a warm courier van is a bigger problem for a mixed vial than for dry powder

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u/nightowl_injector1 point·14 days ago

time-at-temperature integral is the dose, not just peak temperature

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u/cesar_teixeiraOP2 points·14 days ago

data logger is the standard, gut feeling is not

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u/cesar_teixeiraOP12 points·15 days ago

Customs clearance took 24 days. Package sat unrefrigerated during that. Powder tested clean after, reconstituted solution probably would not have.

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u/marta_ilunga5 points·14 days ago

Yeah, data logger is the only acceptable proof.

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u/transit_variance-12 points·14 days ago

Not convinced. The evidence does not support that reading.

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u/milan_mensah5 points·15 days ago

excursion claims need a logger trace or a photo at unboxing, not "it felt warm"

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u/milos_vestergaard3 points·14 days ago

stability after excursion is not zero, it is dose-dependent

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About c/coldchain

Temperature and stability in the real world: what an excursion actually costs you, why lyophilised powder is far more forgiving than reconstituted solution, how to read a logger CSV, and how to photograph a failed shipment so the conversation with the vendor is short.

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