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c/coldchain·submitted 6 months ago by u/hamza_weiss

the lyophilised question that gets asked weekly, answered properly

PSAbranch of 7 comments

the lyophilised question that gets asked weekly, answered properly, and I am aware this is a minority view on this board. Gel packs are designed for a duty cycle. A liquid pack at the end of a longer-than-expected transit is a pack behaving as specified, not evidence of an excursion in the vial. A transit temperature…

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7 comments, started 6 months ago
u/low_appetite_lisa18 points·6 months ago

You cannot infer potency from a temperature record. The record tells you what happened to the box; only a test tells you what happened to the material.

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u/sequence_checkerresearch peptides8 points·6 months ago

You cannot infer potency from a temperature record.

This is the distinction that resolves most threads here — powder and solution are different problems.

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u/emeka_beaulieu3 points·6 months ago

This is the distinction that resolves most threads here — powder and solution are different problems.

Agreed, and a logger costs less than the vial you are worrying about.

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u/hugo_bergstrom2 points·6 months ago

powder at room temperature for a few days is usually a non-event

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u/source_or_silence2 points·6 months ago

Is this a line they hold in regional stock or is it shipping from origin?

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u/hamza_weissOP1 point·6 months ago

Kept a vial at room temperature for eleven days by accident. Tested it out of guilt. It was fine.

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u/bence_ibarra4 points·6 months ago

the excursion that matters is the one after reconstitution

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Temperature and stability in the real world: what an excursion actually costs you, why lyophilised powder is far more forgiving than reconstituted solution, how to read a logger CSV, and how to photograph a failed shipment so the conversation with the vendor is short.

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