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c/coldchain·submitted 2 months ago by u/osman_brandt

[PSA] cold chain is not what most of this community thinks it is

PSAbranch of 8 comments

cold chain is not what most of this community thinks it is, written plainly and without the jargon that usually swallows this topic. What actually matters, in order, because these threads always start at the wrong end. State first: dry powder is comparatively robust, reconstituted solution is not. Most of the anxiety…

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8 comments, started 2 months ago
u/mod_cold_roomMOD82 points·2 months ago

Left up and added to the lane table. Origin, destination and month were all included, which is all we ask.

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u/sten_palacios26 points·2 months ago

powder at room temperature for a few days is usually a non-event

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u/mod_cold_roommod · c/coldchain7 points·2 months ago

Gel pack fully liquid on arrival, powder tested 97.7% against a claimed 97.0% afterwards. The pack had done its job for as long as it was designed to.

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u/split_dose_sceptic3 points·2 months ago

ask what storage condition the stability statement was written against

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u/tidy_vialdrawer_watch2863 points·2 months ago

I would not freeze it in solution. That is a different failure mode and a worse one.

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u/osman_brandtOP23 points·2 months ago

Wrote the reconstitution date on the vial for the first time last year. Have never once since wondered how old a solution is.

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u/jarno_karlsen51 points·2 months ago·edited

Small fix — refrigerated, not frozen, once it is in solution.

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u/gustav_vermeulen12 points·2 months ago

Do you know what storage condition the stability statement covers?

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