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c/coldchain·posted 10 days ago by u/marit_laurent

[PSA] never the fridge door. the door is the warmest wobbliest shelf you own

PSA Slow Clap ×1

Been lurking in c/coa for about 15 months and finally have something worth posting.

Short version: week 75, 1.7mg, and cold chain is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 21 threads, and the answers split roughly down the middle.

What I actually want to know is whether the people saying it does not matter have measured it, or whether it is just repeated confidently. Happy to be told I am overthinking this — I probably am — but I would rather overthink it now than at week 69.

848 up / 213 down80% upvoted15 commentsid 1mypqz19 Jul 2026

15 comments

12 in this archive, depth 3

best — the order this archive was captured in

u/split_dose_sceptic67 points·9 days ago

no tracking numbers, no full addresses, no label photos — instant removal

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u/iman_castellanos65 points·9 days ago

excursion claims need a logger trace or a photo at unboxing, not "it felt warm"

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u/jarno_adeyemi16 points·9 days ago

lyophilised powder is far more forgiving than reconstituted solution

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u/chidi_yilmaz18 points·9 days ago

lyophilised powder is far more forgiving than reconstituted solution

Disagree on that part. 93.7% and 99.3% on the same vial is normal.

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u/sequence_checkerresearch peptides42 points·9 days ago

time-at-temperature integral is the dose, not just peak temperature

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u/marit_laurentOP20 points·8 days ago

time-at-temperature integral is the dose, not just peak temperature

Disagree on that part. 97.4% and 99.3% on the same vial is normal.

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u/chidi_yilmaz11 points·8 days ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/bence_ibarra19 points·10 days ago
post the spreadsheet
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u/osman_brandt6 points·10 days ago

data logger is the standard, gut feeling is not

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u/sten_palacios21 points·10 days ago·edited

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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About c/coldchain

Temperature and stability in the real world: what an excursion actually costs you, why lyophilised powder is far more forgiving than reconstituted solution, how to read a logger CSV, and how to photograph a failed shipment so the conversation with the vendor is short.

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