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c/bloodwork·posted 13 days ago by u/santiago_szabo

[Results] hs-CRP halved before the scale moved much

Results Well Actually ×4 Cold Box ×2

Long-ish post, sorry. tl;dr at the bottom.

I have been tracking bloodwork against ApoB for 11 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.

Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.

tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.

1,766 up / 39 down98% upvoted54 commentsid 2ihbas17 Jul 2026

54 comments

27 in this archive, depth 5

best — the order this archive was captured in

u/emil_okwuosa262 points·12 days ago

Same lab both times?

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u/liver_enzyme_liz204 points·12 days ago
post the spreadsheet
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u/lipid_panel_larryMOD110 points·12 days ago

Retitled to remove editorialising. Put the evidence in the body.

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u/transit_variance48 points·11 days ago

Disagree. What you are describing is consistent with eGFR, not with what you concluded.

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u/no_refunds_nr131 points·12 days ago·edited

Not convinced. The evidence does not support that reading.

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[deleted]85 points·12 days ago

[deleted]

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u/bence_zamora139 points·12 days ago

ApoB over LDL-C, that is the hierarchy

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u/santiago_szaboOP106 points·12 days ago

Ferritin tanked from 17 to 25. Small appetite, reduced iron intake, nobody was testing it until I asked.

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u/ravi_sandvik34 points·12 days ago

ALT is where the fatty-liver story shows up first

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u/lipid_panel_larrybloodwork110 points·12 days ago

ALT is where the fatty-liver story shows up first

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u/noor_cardoso129 points·12 days ago

You have restated the marketing copy. What is the actual substance here.

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u/kofi_balogun91 points·12 days ago

Yeah, baseline matters more than any later number.

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u/ravi_sandvik24 points·11 days ago

Yeah, baseline matters more than any later number.

Yes, exactly this, and it is the bit that took me 86 weeks to accept.

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u/yara_boateng17 points·11 days ago

HOMA-IR is crude but free and useful for tracking

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u/santiago_szaboOP13 points·11 days ago

Strongly agree. ALT is where you catch the liver story early.

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u/elin_trevino10 points·11 days ago

You have restated the marketing copy. What is the actual substance here.

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u/mariam_mensa0 points·11 days ago

Ferritin tanked from 19 to 11. Small appetite, reduced iron intake, nobody was testing it until I asked.

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u/anya_rautio1 point·10 days ago

Same lab both times?

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u/hugo_pires40 points·11 days ago

Half-life is about 168 hours, so steady state lands around week 22–5. Practical consequence: what you feel in week 1 is not what that dose does.

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u/neha_rahimi33 points·11 days ago

Is that fasted?

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u/rekha_mwangi26 points·11 days ago

eGFR noise during rapid loss is expected

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u/coring_the_stopper8 points·11 days ago

eGFR noise during rapid loss is expected

Disagree on that part. 96.8% and 96.2% on the same vial is normal.

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u/diego_sorensen30 points·11 days ago

This is correct. ApoB is the better marker.

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u/chidi_abubakar20 points·11 days ago

post reference ranges with your numbers, units differ by country and lab

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u/employer_carveout7 points·11 days ago

the 23 month eGFR check is the routine

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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