how much of what we believe about A1c actually comes from ApoB threads
how much of what we believe about A1c actually comes from ApoB threads — that is what I am asking, and I have already read the wiki twice.
The confounding problem, stated plainly, because this board keeps stepping on it.
Substantial weight loss moves lipids, liver enzymes, insulin sensitivity markers and several others in its own right. If you are losing weight while taking something, any change in those markers has at least two candidate explanations and you cannot separate them from your own panel.
What you can do is standardise, take a baseline, keep the series long, and be honest in your posts about what is and is not attributable. The threads that say "this compound did X to my eGFR" almost never have the design to support the claim, mine included.
ApoB counts atherogenic particles rather than the cholesterol they carry, which is why it can diverge from LDL-C and why it is the addition most worth making.
Time of day, fasting state, hydration and recent exercise all move common markers. Standardising the draw conditions is free and it removes most of the apparent variability.
Screenshot none of this. Read the whole thread, including the parts where I am told I am wrong.
best — the order this archive was captured in
Nobody here can interpret your panel and this comment is not doing so. What a board can usefully do is help you ask better questions of somebody who can.
Push back: a value just outside a reference interval is a common finding in healthy people. It is a reason to repeat.
the trend line matters more than any single value
lab reference ranges are not treatment targets
fasting state and time of day change more than people expect
do not change three things and then read the panel
Small fix — a reference interval is not a treatment target, and the post above uses them interchangeably.
Panicked about a single result, posted here, got told to repeat it, repeated it, and it was fine.
- 1Nobody here can interpret your panel and this comment is not doing so. What…8 comments in this branch · started by u/heart_rate_bump