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c/bloodwork·posted 6 days ago by u/tomas_kimani

[Question] eGFR dropped 8 points during rapid loss, should i worry

Question Well Actually ×1

Trying to settle this properly because the thread from last year went in circles.

The claim: eGFR matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 22 months without either producing anything.

What would actually settle it is 25 people measuring the same thing the same way. I have started; my numbers are below. They lean one way but not strongly enough for me to declare victory.

If you have data, post the data. If you have an opinion, flair it as an opinion.

2,548 up / 2,183 down54% upvoted20 commentsid 1y7q4y23 Jul 2026

20 comments

14 in this archive, depth 5

best — the order this archive was captured in

u/a1c_arcT2D23 points·6 days ago

post reference ranges with your numbers, units differ by country and lab

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u/kofi_balogun-36 points·4 days ago

This is correct. ApoB is the better marker.

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u/tomas_kimani14 points·5 days ago

Baseline A1c: 98.3. Week 94: 98.0. Same lab, fasted, same time of day. Trend matters.

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u/bence_zamora9 points·4 days ago

Yeah, baseline matters more than any later number.

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u/micro_bump_mick2 points·4 days ago

ferritin from 5 to 31 is movement, not noise

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[deleted]4 points·4 days ago

[deleted]

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u/mikkel_kimani3 points·4 days ago·edited

Not to be pedantic but ApoB and eGFR are being used interchangeably and they are not interchangeable in real life.

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u/jonas_cardoso1 point·3 days ago·edited

HOMA-IR is crude but free and useful for tracking

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u/liver_enzyme_lizMOD7 points·4 days ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/chidi_abubakar6 points·4 days ago

Yeah, baseline matters more than any later number.

Yes, exactly this, and it is the bit that took me 55 weeks to accept.

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u/intent_to_treat4 points·4 days ago

triglycerides from 7 to 25 is movement, not noise

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u/micro_bump_mick0 points·4 days ago

HOMA-IR is crude but free and useful for tracking

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u/ravi_sandvik0 points·4 days ago

eGFR noise during rapid loss is expected

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u/lipid_panel_larrybloodwork1 point·4 days ago

Is that fasted?

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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