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c/bloodwork·submitted 1 year ago by u/lina_almeida

baseline labs: the version I wish someone had shown me in week 1

Concerningbranch of 8 comments

baseline labs: the version I wish someone had shown me in week 1. Posting the boring middle of the process, because the internet is full of the start and the end and nothing else. Nobody here can interpret your panel and this comment is not doing so. What a board can usefully do is help you ask better questions of…

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8 comments, started 1 year ago
u/baseline_drifteranalytical211 points·1 year ago

How to make a panel worth comparing, which is most of the value people leave on the table.

Standardise the conditions: same lab, same fasting state, same rough time of day, same point in the week, similar hydration. Take a baseline before you change anything. Repeat any surprising value before acting on it. Change one thing at a time if you want to attribute anything to it.

Do that and a year of panels is a trend. Skip it and a year of panels is a collection of unrelated mornings, which is what most of the alarmed posts here are actually describing.

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u/vito_chowdhury118 points·1 year ago

Careful — that is a question for whoever ordered the panel, and nobody in this thread can answer it responsibly.

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u/jarno_karlsen142 points·1 year ago

Draw at the same point in the week now, fasting, same lab. The noise dropped enormously once I standardised.

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u/flair_enthusiast89 points·1 year ago

Substantial weight loss independently moves lipids, liver enzymes and several other markers. Attributing a change to a compound while losing weight is confounded by design.

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u/lina_almeidaOP-19 points·1 year ago

Substantial weight loss independently moves lipids, liver enzymes and several other markers.

flair_enthusiast is right that a reference interval is not a target. It is a description of a population.

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u/laila_yilmaz47 points·1 year ago

Yes — same lab, same fasting state, same rough time of day, or the comparison is doing nothing.

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u/lina_almeidaOP75 points·1 year ago

That is a non-fasting value and the interval you are comparing it against is a fasting one.

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u/forest_plot_fionastats34 points·1 year ago·edited

That is a non-fasting value and the interval you are comparing it against is a fasting one.

Agreed — and standardising the draw conditions is the cheapest improvement available.

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