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c/bloodwork·posted 1 year ago by u/nikhil_asante

[Discussion] can we stop arguing about eGFR until somebody posts a number

Discussion Slow Clap ×9 Well Actually ×2 Clean Column ×1

can we stop arguing about eGFR until somebody posts a number. If this has been answered properly somewhere, link me and I will delete.

Draw at the same point in the week now, fasting, same lab. The noise dropped enormously once I standardised.

Added ApoB to the panel after a thread here. It told me something the standard lipid panel had been hiding.

Compared two draws across two labs and spent a week worrying before finding out the assays were different.

Research-use-only material is not approved for human use and nothing here should be read as a recommendation to use it.

25,985 up / 21,886 down54% upvoted39 commentsid 11klpo16 Aug 2024

39 comments

16 in this archive, depth 3

best — the order this archive was captured in

u/step_therapy_s776 points·1 year ago

Different laboratories use different assay platforms with different calibration. Comparing across labs adds a systematic offset that is invisible on the report.

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u/micro_bump_mick469 points·1 year ago

Same lab as the previous draw?

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u/cormac_erdogan402 points·1 year ago

Same view — ApoB if you add one thing. It answers a question the standard panel only gestures at.

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u/intent_to_treat122 points·1 year ago

Brought the whole set to my clinician rather than one flagged value. Completely different conversation.

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u/santiago_szabo149 points·1 year ago

one measurement is a point, two is a line, three is a trend

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u/nikhil_asanteOP75 points·1 year ago

hydration status moves a surprising number of markers

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u/pavel_nkemelu-14 points·1 year ago

What did the repeat show?

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u/karl_fischer_kev-21 points·1 year ago

Careful — that is a question for whoever ordered the panel, and nobody in this thread can answer it responsibly.

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u/noor_cardoso0 points·1 year ago

Have you taken this to whoever ordered it?

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u/a1c_arcMOD205 points·1 year ago

Left up. It is a question about how to compare panels, not a request for interpretation.

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u/blank_injection99 points·1 year ago·edited

Left up.

This is the sentence to read before anybody panics about a single value.

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u/intent_to_treat23 points·1 year ago

My hs-CRP moved and I spent a fortnight convinced I knew why. The repeat six weeks later was back in range and I had changed nothing.

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u/baseline_drifteranalytical47 points·1 year ago

baseline before you start is worth more than any later panel

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u/nnt_nate177 points·1 year ago

bring the numbers to someone qualified to read them

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u/diego_almeida46 points·1 year ago

Substantial weight loss independently moves lipids, liver enzymes and several other markers. Attributing a change to a compound while losing weight is confounded by design.

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u/karl_fischer_kev16 points·1 year ago

ask whether the lab changed its assay between your two draws

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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